Non-GLP Toxicology Studies
For pharmaceutical and biotech companies, even after the successful identification of an active molecule against a disease target, many drugs fail to ever reach the market because of unacceptable adverse effects. By identifying possible safety concerns earlier in the drug development process, JOINN provides services to assess the genotoxic and cardiovascular toxic potential of candidate molecules.
Single-Dose and Repeat-Dose Toxicity Studies:
Predict toxicity and toxic target with fast speed and high quality (small or large animals）
Genotoxicity Studies:
Ames Assay, Micronucleus Test
Cardiotoxic Studies:
Langendorff Isolated Perfused Heart System (ECG, LVP), action potentials records of cardiac papillary muscles (APD30/APD90), hERG Channel Assay
Reproductive Toxicity Studies:
Whole Embryo Culture